Xudong Ge

CAST FACULTY

Assistant Director and Scientist, CAST

 

Xudong Ge is an Assistant Director, Center for Advanced Sensor Technology and a Scientist, Department of Chemical and Biochemical Engineering University of Maryland, Baltimore County.

KNOWN FOR

Optical CO2 Sensors  Noninvasive Bioprocess Monitoring  Low‑Cost Sensors

Email

 Xudong Ge

Signature Work ↓  Publications ↓

IN HIS WORDS

“Opioid-related death is a serious problem for the country.”

Xudong Ge, on CAST’s wearable CO2 sensor for opioid overdose, in UMBC News

SIGNATURE WORK

Global Impact

 
Miniature CO2 sampler on a newborn's skin

01  CARE FOR NEWBORNS

Neonatal CO2 Monitor

A small cup on the skin collects the CO2 that diffuses out, and the reading comes from how fast it builds up. In a NICU study with preterm infants, most readings fell within 4 mmHg of blood gas values. Ge later led a point-of-care version of the monitor.

No heating  vs. skin heated to about 43°C

02  NONINVASIVE SENSING

Low-Cost Optical CO2 Sensor

A sensor patch inside a flask or bioreactor changes its fluorescence with dissolved CO2, and a low-cost reader outside picks up the signal through the clear wall.

No probe  inserted into the culture
Transparent flask with an optical sensor stack
High-throughput mini bioreactor array

03  FASTER CELL CULTURE

High-Throughput Bioreactor

Mini stirred-tank bioreactors run side by side, each monitored by optical sensors. Tests showed the sensor patches had no apparent effect on cell metabolism, so many culture conditions can be tried at once.

12  mini bioreactors run and monitored at once

ALSO WORKS ON

Bio‑MOD  Glucose Binding Protein Sensors  Wood Microfluidics

Selected Publications

 

MOST CITED

2006
Ge X, Hanson M, Shen H, Kostov Y, Brorson KA, Frey DD, Moreira AR, Rao G
JOURNAL OF BIOTECHNOLOGY · 122:293–306
2018
Adiga R, Al-adhami M, Andar A, … Frey DD, Ge X, … Rao G, … Zuber A
NATURE BIOMEDICAL ENGINEERING · 2:675–686

LATEST

2025
Kadolkar R, Kumar V, Thole A, … Ge X, Frey DD, … Rao G
BIOTECHNOLOGY AND BIOENGINEERING · 122:3249–3265
2024
Rahmatnejad V, Tolosa M, Ge X, Rao G
BIOTECHNOLOGY LETTERS · 46:983–996