Yordan Kostov

Yordan V. Kostov is an Assistant Director, Center for Advanced Sensor Technology Research and an Research Associate Professor, Department of Chemical & Biochemical Engineering University of Maryland, Baltimore County.






Title: Research Associate Professor, CAST


  • Odessa Polytechnical Institute(Ukraine) EE M.S. 1987
  • Bulgarian Acad. of Sci. (Bulgaria) EE/ChemE Ph.D. 1995
  • University of Hannover, Germany Fluorescent sensor studies 1995 (post-doc)
  • University of Maryland Biotechnology Institute Fluorescent sensor studies 2000 (post-doc)


  • 2004-present: Assistant Director, Center for Advanced Sensor Technology, UMBC.
  • 2000-present: Research Assistant Professor, Dept. of Chemical and Biochemical Engineering, UMBC.
  • 1999-2000: Postdoctoral Fellow, Medical Biotechnolgy Center, UMBI.
  • 1994-1999: Assistant Professor, Dept. of Biotechnics, Technical University – Sofia, Bulgaria.
  • 1993-1994: Design Engineer, Central Laboratory for Bioinstrumentation and Automation, Bulgarian Academy of Sciences, Bulgaria.
  • 1987-1989: RF Microcircuits technology Engineer, Institute “Electron” – Sofia, Bulgaria

Research Activities

Optical and electronic instrumentation design, Taught Electrical Engineering elective course on Biomedical sensors. Participated in SBIR review panels.

Awards and Memberships

  • Gaden Award for the most influential paper in biotechnology for 2001, First Author
  • Award “For outstanding achievements” in the competition “Bulgarian young inventor ’97”
  • Deutscher Akademischer Austauschdienst (DAAD, Germany) Fellowship, 1995
  • Bulgarian Ministry of Education Golden Medal for Academic Achievements, 1987

Recent Publications

Google Scholar

Selected Publications

  • Hanson, M.A., Ge, X., Kostov, Y., Brorson, K.A., Moreira, A.R., Rao, G. (2007) Comparisons of optical pH and Dissolved Oxygen sensors with traditional electrochemical probes during mammalian cell culture. Biotechnol.Bioeng. 97, 833-841
  • Smith, D., Kostov, Y., Rao, G. (2007) SPCE-Based Sensors. 1. Oxygen Sensing Using Surface-Plasmon Coupled Emission from Ruthenium Probes. Sensors and Actuators B 127, 432-440
  • Petrova S., Kostov Y., Jeffris K., Rao G. (2007) Optical Ratiometric sensor for alcohol measurements. Anal. Letters 40, 715-727
  • Harms, P., Kostov, Y., Ram, A., French, J.A., Rao, G. (2006) Design of a 24 Station Microbioreactor Platform Biotechnol. Bioeng. 93, 6-13.
  • Sin, A., Chin, K.C., Jamil, M.F., Kostov, Y., Rao, G., Shuler, M.L. (2004) The Design and Fabrication of Three Chamber Microscale Cell Culture Analog Devices with Integrated Dissolved Oxygen Sensors, Biotechnol. Prog. 20, 338-345.
  • Ge, X., Kostov, Y., Rao, G. (2004) Low-Cost Noninvasive Optical CO2 Sensing System for Fermentation and Cell culture, Biotechnol.Bioeng. 89, 329-334
  • Kostov, Y., Rao, G. (2003) Ratio measurements in oxygen determinations: wavelength ratiometry, lifetime discrimination and polarization detection. Sens. Actuators B 90, 139-142.
  • Harms, P., Kostov, Y., Rao, G. (2002) Bioprocess monitoring. Curr. Opinion Biotechnol. 13, 124-127
  • Kostov, Y., Harms, P., Rao, G. (2001) Ratiometric sensing using dual-frequency lifetime discrimination. Anal. Biochem. 297, 105-108.
  • Kostov Y., Harms P., Randers-Eichhorn L., Rao G. (2001) Low-cost microbioreactor for high-throughput bioprocessing. Biotechnology and Bioengineering, 72, 346-352.
  • Kostov Y., Rao G. (2000) Low-cost optical instrumentation for biomedical measurements. Rev. Sci. Instr., 70, 4361-4374.
  • Kostov Y., Rao. G. (1999) Simple low-cost device for fluorescence ratiometric measurements. Rev. Sci. Instr., 70, 4466-4470.